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Mutations in HIV-1 Reverse Transcriptase Affect the Errors Made in a Single Cycle of Viral Replication

The genetic variation in HIV-1 in patients is due to the high rate of viral replication, the high viral load, and the errors made during viral replication. Some of the mutations in reverse transcriptase (RT) that alter the deoxynucleoside triphosphate (dNTP)-binding pocket, including those that conf...

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書誌詳細
主要な著者: Abram, Michael E., Ferris, Andrea L., Das, Kalyan, Quinoñes, Octavio, Shao, Wei, Tuske, Steven, Alvord, W. Gregory, Arnold, Eddy, Hughes, Stephen H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054409/
https://ncbi.nlm.nih.gov/pubmed/24760888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00302-14
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