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Mutations in HIV-1 Reverse Transcriptase Affect the Errors Made in a Single Cycle of Viral Replication
The genetic variation in HIV-1 in patients is due to the high rate of viral replication, the high viral load, and the errors made during viral replication. Some of the mutations in reverse transcriptase (RT) that alter the deoxynucleoside triphosphate (dNTP)-binding pocket, including those that conf...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Microbiology
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054409/ https://ncbi.nlm.nih.gov/pubmed/24760888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00302-14 |
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