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Analysis of the Zidovudine Resistance Mutations T215Y, M41L, and L210W in HIV-1 Reverse Transcriptase

Although anti-human immunodeficiency virus type 1 (HIV-1) therapies have become more sophisticated and more effective, drug resistance continues to be a major problem. Zidovudine (azidothymidine; AZT) was the first nucleoside reverse transcriptase (RT) inhibitor (NRTI) approved for the treatment of...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Boyer, Paul L., Das, Kalyan, Arnold, Eddy, Hughes, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649230/
https://ncbi.nlm.nih.gov/pubmed/26324274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05069-14
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