Systematic biases in DNA copy number originate from isolation procedures

BACKGROUND: The ability to accurately detect DNA copy number variation in both a sensitive and quantitative manner is important in many research areas. However, genome-wide DNA copy number analyses are complicated by variations in detection signal. RESULTS: While GC content has been used to correct...

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Main Authors: van Heesch, Sebastiaan, Mokry, Michal, Boskova, Veronika, Junker, Wade, Mehon, Rajdeep, Toonen, Pim, de Bruijn, Ewart, Shull, James D, Aitman, Timothy J, Cuppen, Edwin, Guryev, Victor
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054094/
https://ncbi.nlm.nih.gov/pubmed/23618369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-4-r33
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