Efficient Double Fragmentation ChIP-seq Provides Nucleotide Resolution Protein-DNA Binding Profiles

Immunoprecipitated crosslinked protein-DNA fragments typically range in size from several hundred to several thousand base pairs, with a significant part of chromatin being much longer than the optimal length for next-generation sequencing (NGS) procedures. Because these larger fragments may be non-...

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Detalhes bibliográficos
Main Authors: Mokry, Michal, Hatzis, Pantelis, de Bruijn, Ewart, Koster, Jan, Versteeg, Rogier, Schuijers, Jurian, van de Wetering, Marc, Guryev, Victor, Clevers, Hans, Cuppen, Edwin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994895/
https://ncbi.nlm.nih.gov/pubmed/21152096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015092
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