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The Physical Association of the P2Y12 Receptor with PAR4 Regulates Arrestin-Mediated Akt Activation

It is now well accepted that protease activated receptor (PAR) 1 and PAR4 have differential roles in platelet activation. PAR4, a low-affinity thrombin receptor in human platelets, participates in sustained platelet activation in a P2Y12-dependent manner; however, the mechanisms are not defined. Our...

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Hlavní autoři: Khan, Aasma, Li, Dongjun, Ibrahim, Salam, Smyth, Emer, Woulfe, Donna S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054002/
https://ncbi.nlm.nih.gov/pubmed/24723492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.091595
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