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The Physical Association of the P2Y12 Receptor with PAR4 Regulates Arrestin-Mediated Akt Activation
It is now well accepted that protease activated receptor (PAR) 1 and PAR4 have differential roles in platelet activation. PAR4, a low-affinity thrombin receptor in human platelets, participates in sustained platelet activation in a P2Y12-dependent manner; however, the mechanisms are not defined. Our...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054002/ https://ncbi.nlm.nih.gov/pubmed/24723492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.091595 |
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