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Arrestin-2 Differentially Regulates PAR4 and ADP Receptor Signaling in Platelets

Arrestins can facilitate desensitization or signaling by G protein-coupled receptors (GPCR) in many cells, but their roles in platelets remain uncharacterized. Because of recent reports that arrestins can serve as scaffolds to recruit phosphatidylinositol-3 kinases (PI3K)s to GPCRs, we sought to det...

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Détails bibliographiques
Auteurs principaux: Li, Dongjun, D'Angelo, Lauren, Chavez, Massiel, Woulfe, Donna S.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030382/
https://ncbi.nlm.nih.gov/pubmed/21106537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.118018
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