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Heterodimerization with the Prostacyclin Receptor Triggers Thromboxane Receptor Relocation to Lipid Rafts
OBJECTIVE: Prostacyclin and thromboxane mediate opposing cardiovascular actions through receptors termed IP and TP, respectively. When dimerized with IP, the TP shifts to IP-like function. IP localizes to cholesterol-enriched membrane rafts but TP and IPTP heterodimer localization is not defined. We...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533363/ https://ncbi.nlm.nih.gov/pubmed/23162015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300536 |
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