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Aortic Valve Calcification is Mediated by a Differential Response of Aortic Valve Interstitial Cells to Inflammation

BACKGROUND: While calcific aortic stenosis is common, calcification of the other three heart valves is not. The aortic valve interstitial cell (VIC) has been implicated in the pathogenesis of aortic stenosis. Pro-inflammatory stimulation of aortic VICs induces an osteogenic and inflammatory phenotyp...

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Main Authors: Venardos, Neil, Nadlonek, Nicole A., Zhan, Qiong, Weyant, Michael J., Reece, T. Brett, Meng, Xianzhong, Fullerton, David A.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053510/
https://ncbi.nlm.nih.gov/pubmed/24746950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2014.03.051
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