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Interleukin-1 Beta Induces an Inflammatory Phenotype in Human Aortic Valve Interstitial Cells Through Nuclear Factor Kappa Beta

BACKGROUND: Mechanisms of inflammation have been implicated in the pathogenesis of aortic stenosis. When stimulated, human aortic valve interstitial cells (AVICs) have been shown to become inflammatory cells. Increased levels of interleukin (IL)-1β have been found in the leaflets of stenotic aortic...

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Detalhes bibliográficos
Main Authors: Nadlonek, Nicole, Lee, Joon H., Reece, T. Brett, Weyant, Michael J., Cleveland, Joseph C., Meng, Xianzhong, Fullerton, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833085/
https://ncbi.nlm.nih.gov/pubmed/23735716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2013.04.013
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