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Radiation Induces Osteogenesis in Human Aortic Valve Interstitial Cells

OBJECTIVE: Irradiation of the chest or chest wall has been shown to caause calcific aortic stenosis. However, the mechanisms are unknown. Aortic valve interstitial cells (AVICs) have been implicated in the pathogenesis of aortic stenosis; they have been shown to change from the phenotype of a myofib...

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Autors principals: Nadlonek, Nicole A, Weyant, Michael J, Yu, Jessica A, Cleveland, Joseph C, Reece, T Brett, Meng, Xianzhong, Fullerton, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665422/
https://ncbi.nlm.nih.gov/pubmed/23026565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2012.08.041
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