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MMP-12–Induced Pro-osteogenic Responses in Human Aortic Valve Interstitial Cells

BACKGROUND: Calcific aortic valve disease (CAVD) is an age-related and slowly progressive valvular disorder. Overexpression of matrix metalloproteinase 12 (MMP-12) has been found in atherosclerosis, stiffed vascular tissue, and calcified aortic valves. We hypothesized that MMP-12 may induce the pro-...

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Detalhes bibliográficos
Publicado no:J Surg Res
Main Authors: Deng, Xin-sheng, Meng, Xianzhong, Li, Fei, Venardos, Neil, Fullerton, David, Jaggers, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791591/
https://ncbi.nlm.nih.gov/pubmed/30691826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2018.09.005
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