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High Runx1 levels promote a reversible more differentiated cell-state in hair follicle stem cells during quiescence

Quiescent hair follicle (HF) bulge stem cells (SCs) differentiate to early progenitor (EP) hair germ (HG) cells, which divide to produce transit-amplifying (TA) matrix cells. EPs can revert to SCs upon injury, but whether this de-differentiation occurs in normal HF homeostasis (hair cycle), and the...

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Autors principals: Lee, Song Eun, Sada, Aiko, Zhang, Meng, McDermitt, David J., Lu, Shu Yang, Kemphues, Kenneth J., Tumbar, Tudorita
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052453/
https://ncbi.nlm.nih.gov/pubmed/24462289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.039
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