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Runx1 Directly Promotes Proliferation of Hair Follicle Stem Cells and Epithelial Tumor Formation in Mouse Skin

Runx1/AML1 is a transcription factor implicated in tissue stem cell regulation and belongs to the small Runx family of cancer genes. In the hair follicle (HF), Runx1 epithelial deletion in morphogenesis impairs normal adult hair homeostasis (cycle) and blocks adult hair follicle stem cells (HFSCs) i...

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Detalhes bibliográficos
Main Authors: Hoi, Charlene S. L., Lee, Song Eun, Lu, Shu-Yang, McDermitt, David J., Osorio, Karen M., Piskun, Caroline M., Peters, Rachel M., Paus, Ralf, Tumbar, Tudorita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863705/
https://ncbi.nlm.nih.gov/pubmed/20308320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01308-09
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