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Quantitative proliferation dynamics and random chromosome segregation of hair follicle stem cells

Regulation of stem cell (SC) proliferation is central to tissue homoeostasis, injury repair, and cancer development. Accumulation of replication errors in SCs is limited by either infrequent division and/or by chromosome sorting to retain preferentially the oldest ‘immortal' DNA strand. The fre...

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Detalhes bibliográficos
Main Authors: Waghmare, Sanjeev K, Bansal, Rajat, Lee, Jayhun, Zhang, Ying V, McDermitt, David J, Tumbar, Tudorita
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374848/
https://ncbi.nlm.nih.gov/pubmed/18401343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.72
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