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Runx1 and p21 synergistically limit the extent of hair follicle stem cell quiescence in vivo

Mechanisms of tissue stem cell (SC) quiescence control are important for normal homeostasis and for preventing cancer. Cyclin-dependent kinase inhibitors (CDKis) are known inhibitors of cell cycle progression. We document CDKis expression in vivo during hair follicle stem cell (HFSC) homeostasis and...

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Detalhes bibliográficos
Main Authors: Lee, Jayhun, Hoi, Charlene S. L., Lilja, Karin C., White, Brian S., Lee, Song Eun, Shalloway, David, Tumbar, Tudorita
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606971/
https://ncbi.nlm.nih.gov/pubmed/23487742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213015110
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