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High Runx1 Levels Promote a Reversible, More-Differentiated Cell State in Hair-Follicle Stem Cells during Quiescence

Quiescent hair follicle (HF) bulge stem cells (SCs) differentiate to early progenitor (EP) hair germ (HG) cells, which divide to produce transit-amplifying matrix cells. EPs can revert to SCs upon injury, but whether this dedifferentiation occurs in normal HF homeostasis (hair cycle) and the mechani...

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Detalhes bibliográficos
Main Authors: Song Eun Lee, Aiko Sada, Meng Zhang, David J. McDermitt, Shu Yang Lu, Kenneth J. Kemphues, Tudorita Tumbar
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014-02-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124713007973
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