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In vivo Discovery of Immunotherapy Targets in the Tumor Microenvironment

Recent clinical trials showed that targeting of inhibitory receptors on T cells induces durable responses in a subset of cancer patients, despite advanced disease. However, the regulatory switches controlling T cell function in immunosuppressive tumors are not well understood. Here we show that such...

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書誌詳細
主要な著者: Zhou, Penghui, Shaffer, Donald R., Arias, Diana A. Alvarez, Nakazaki, Yukoh, Pos, Wouter, Torres, Alexis J., Cremasco, Viviana, Dougan, Stephanie K., Cowley, Glenn S., Elpek, Kutlu, Brogdon, Jennifer, Lamb, John, Turley, Shannon, Ploegh, Hidde L., Root, David E., Love, J. Christopher, Dranoff, Glenn, Hacohen, Nir, Cantor, Harvey, Wucherpfennig, Kai W.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052214/
https://ncbi.nlm.nih.gov/pubmed/24476824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12988
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