In vivo Discovery of Immunotherapy Targets in the Tumor Microenvironment

Recent clinical trials showed that targeting of inhibitory receptors on T cells induces durable responses in a subset of cancer patients, despite advanced disease. However, the regulatory switches controlling T cell function in immunosuppressive tumors are not well understood. Here we show that such...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhou, Penghui, Shaffer, Donald R., Arias, Diana A. Alvarez, Nakazaki, Yukoh, Pos, Wouter, Torres, Alexis J., Cremasco, Viviana, Dougan, Stephanie K., Cowley, Glenn S., Elpek, Kutlu, Brogdon, Jennifer, Lamb, John, Turley, Shannon, Ploegh, Hidde L., Root, David E., Love, J. Christopher, Dranoff, Glenn, Hacohen, Nir, Cantor, Harvey, Wucherpfennig, Kai W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052214/
https://ncbi.nlm.nih.gov/pubmed/24476824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12988
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