Predicting Protein Aggregation during Storage in Lyophilized Solids Using Solid State Amide Hydrogen/Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS)

[Image: see text] Solid state amide hydrogen/deuterium exchange with mass spectrometric analysis (ssHDX-MS) was used to assess the conformation of myoglobin (Mb) in lyophilized formulations, and the results correlated with the extent of aggregation during storage. Mb was colyophilized with sucrose (...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Moorthy, Balakrishnan S., Schultz, Steven G., Kim, Sherry G., Topp, Elizabeth M.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Chemical Society 2014
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051254/
https://ncbi.nlm.nih.gov/pubmed/24816133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500005v
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة