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Photolytic Labeling to Probe Molecular Interactions in Lyophilized Powders

Local side-chain interactions in lyophilized protein formulations were mapped using solid-state photolytic labeling-mass spectrometry (ssPL-MS). Photoactive amino acid analogs (PAAs) were used as probes and either added to the lyophilized matrix or incorporated within the amino acid sequence of a pe...

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Detalhes bibliográficos
Main Authors: Iyer, Lavanya K., Moorthy, Balakrishnan S., Topp, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913734/
https://ncbi.nlm.nih.gov/pubmed/24125175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4004332
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