BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis

During meiosis, DNA damage response (DDR) proteins induce transcriptional silencing of unsynapsed chromatin, including the constitutively unsynapsed XY chromosomes in males. DDR proteins are also implicated in double strand break repair during meiotic recombination. Here, we address the function of...

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Autors principals: Broering, Tyler J., Alavattam, Kris G., Sadreyev, Ruslan I., Ichijima, Yosuke, Kato, Yasuko, Hasegawa, Kazuteru, Camerini-Otero, R. Daniel, Lee, Jeannie T., Andreassen, Paul R., Namekawa, Satoshi H.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050732/
https://ncbi.nlm.nih.gov/pubmed/24914237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311050
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