BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis

During meiosis, DNA damage response (DDR) proteins induce transcriptional silencing of unsynapsed chromatin, including the constitutively unsynapsed XY chromosomes in males. DDR proteins are also implicated in double strand break repair during meiotic recombination. Here, we address the function of...

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Hlavní autoři: Broering, Tyler J., Alavattam, Kris G., Sadreyev, Ruslan I., Ichijima, Yosuke, Kato, Yasuko, Hasegawa, Kazuteru, Camerini-Otero, R. Daniel, Lee, Jeannie T., Andreassen, Paul R., Namekawa, Satoshi H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2014
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050732/
https://ncbi.nlm.nih.gov/pubmed/24914237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311050
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