Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53

The p53 tumor suppressor is controlled by an interactive network of factors that stimulate or inhibit its transcriptional activity. Within that network, Mdm2 functions as the major antagonist of p53 by promoting its ubiquitylation and degradation. Conversely, Tip60 activates p53 through direct assoc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Reed, Sara M, Hagen, Jussara, Tompkins, Van S, Thies, Katie, Quelle, Frederick W, Quelle, Dawn E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2014
Aiheet:
Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049965/
https://ncbi.nlm.nih.gov/pubmed/24621507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28202
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia