Inherited mitochondrial DNA variants can affect complement, inflammation and apoptosis pathways: insights into mitochondrial–nuclear interactions

Age-related macular degeneration (AMD) is the leading cause of vision loss in developed countries. While linked to genetic polymorphisms in the complement pathway, there are many individuals with high risk alleles that do not develop AMD, suggesting that other ‘modifiers’ may be involved. Mitochondr...

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主要な著者: Cristina Kenney, M., Chwa, Marilyn, Atilano, Shari R., Falatoonzadeh, Payam, Ramirez, Claudio, Malik, Deepika, Tarek, Mohamed, Cáceres-del-Carpio, Javier, Nesburn, Anthony B., Boyer, David S., Kuppermann, Baruch D., Vawter, Marquis, Michal Jazwinski, S., Miceli, Michael, Wallace, Douglas C., Udar, Nitin
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049308/
https://ncbi.nlm.nih.gov/pubmed/24584571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu065
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