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Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular Degeneration

BACKGROUND: Mitochondrial dysfunction is associated with the development and progression of age-related macular degeneration (AMD). Recent studies using populations from the United States and Australia have demonstrated that AMD is associated with mitochondrial (mt) DNA haplogroups (as defined by co...

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Détails bibliographiques
Auteurs principaux: Kenney, M. Cristina, Chwa, Marilyn, Atilano, Shari R., Pavlis, Janelle M., Falatoonzadeh, Payam, Ramirez, Claudio, Malik, Deepika, Hsu, Tiffany, Woo, Grace, Soe, Kyaw, Nesburn, Anthony B., Boyer, David S., Kuppermann, Baruch D., Jazwinski, S. Michal, Miceli, Michael V., Wallace, Douglas C., Udar, Nitin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554762/
https://ncbi.nlm.nih.gov/pubmed/23365660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054339
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