Increased expression of ApoE and protection from amyloid-beta toxicity in transmitochondrial cybrids with haplogroup K mtDNA

Mitochondrial (mt) DNA haplogroups, defined by specific single nucleotide polymorphism (SNP) patterns, represent populations of diverse geographic origins and have been associated with increased risk or protection of many diseases. The H haplogroup is the most common European haplogroup while the K...

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Udgivet i:Neurobiol Dis
Main Authors: Thaker, Kunal, Chwa, Marilyn, Atilano, Shari R., Coskun, Pinar, Cáceres-del-Carpio, Javier, Udar, Nitin, Boyer, David S., Jazwinski, S. Michal, Miceli, Michael V., Nesburn, Anthony B., Kuppermann, Baruch D., Kenney, M. Cristina
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922440/
https://ncbi.nlm.nih.gov/pubmed/27109188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.04.005
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