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Polyadenylation inhibition by the triphosphates of deoxyadenosine analogues
The nucleotide substrate specificity of yeast poly(A) polymerase (yPAP) was examined with various ATP analogues of clinical relevance. The triphosphate derivatives of cladribine (2-Cl-dATP), clofarabine (Cl-F-ara-ATP), fludarabine (F-ara-ATP), and related derivatives were incubated with yPAP and (32...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048126/ https://ncbi.nlm.nih.gov/pubmed/18433867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2008.03.010 |
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