Inhibition of ATP Synthase by Chlorinated Adenosine Analogue

8-Chloroadenosine (8-Cl-Ado) is a ribonucleoside analogue that is currently in clinical trial for chronic lymphocytic leukemia. Based on the decline in cellular ATP pool following 8-Cl-Ado treatment, we hypothesized that 8-Cl-ADP and 8-Cl-ATP may interfere with ATP synthase, a key enzyme in ATP prod...

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Bibliografski detalji
Glavni autori: Chen, Lisa S., Nowak, Billie J., Ayres, Mary L., Krett, Nancy L., Rosen, Steven T., Zhang, Shuxing, Gandhi, Varsha
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763632/
https://ncbi.nlm.nih.gov/pubmed/19477165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.05.019
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