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Behavioral Effects of Cocaine Mediated by Nitric Oxide-GAPDH Transcriptional Signaling
Cocaine’s behavioral-stimulant effects derive from potentiation of synaptic signaling by dopamine and serotonin leading to transcriptional alterations in postsynaptic cells. We report that a signaling cascade involving nitric oxide (NO) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mediates c...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047707/ https://ncbi.nlm.nih.gov/pubmed/23719162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.03.021 |
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