Behavioral Effects of Cocaine Mediated by Nitric Oxide-GAPDH Transcriptional Signaling

Cocaine’s behavioral-stimulant effects derive from potentiation of synaptic signaling by dopamine and serotonin leading to transcriptional alterations in postsynaptic cells. We report that a signaling cascade involving nitric oxide (NO) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mediates c...

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Detalhes bibliográficos
Main Authors: Xu, Risheng, Serritella, Anthony V., Sen, Tanusree, Farook, Justin M., Sedlak, Thomas W., Baraban, Jay, Snyder, Solomon H., Sen, Nilkantha
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047707/
https://ncbi.nlm.nih.gov/pubmed/23719162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.03.021
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