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Nitrosylation of GAPDH augments pathological tau acetylation upon exposure to amyloid-β
Acetylation of the microtubule-associated protein tau promotes its polymerization into neurofibrillary tangles that are implicated in the pathology of Alzheimer’s disease (AD). The gaseous neurotransmitter nitric oxide (NO) regulates cell signaling through the nitrosylation of proteins. We found tha...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6371980/ https://ncbi.nlm.nih.gov/pubmed/29559585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aao6765 |
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