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Acute Sterol O-Acyltransferase 2 (SOAT2) Knockdown Rapidly Mobilizes Hepatic Cholesterol for Fecal Excretion

The primary risk factor for atherosclerotic cardiovascular disease is LDL cholesterol, which can be reduced by increasing cholesterol excretion from the body. Fecal cholesterol excretion can be driven by a hepatobiliary as well as a non-biliary pathway known as transintestinal cholesterol efflux (TI...

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Bibliografische gegevens
Hoofdauteurs: Marshall, Stephanie M., Gromovsky, Anthony D., Kelley, Kathryn L., Davis, Matthew A., Wilson, Martha D., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Rudel, Lawrence L., Brown, J. Mark, Temel, Ryan E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047063/
https://ncbi.nlm.nih.gov/pubmed/24901470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098953
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