Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent

Diosgenin exists in some food supplements and herbal medicines and lowers plasma cholesterol by increasing fecal cholesterol excretion. It is believed that diosgenin promotes fecal cholesterol excretion by stimulating biliary cholesterol secretion and decreasing intestinal cholesterol absorption. Ni...

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Bibliografiske detaljer
Main Authors: Temel, Ryan E., Brown, J. Mark, Ma, Yinyan, Tang, Weiqing, Rudel, Lawrence L., Ioannou, Yiannis A., Davies, Joanna P., Yu, Liqing
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666178/
https://ncbi.nlm.nih.gov/pubmed/19141868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800631-JLR200
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