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Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent

Diosgenin exists in some food supplements and herbal medicines and lowers plasma cholesterol by increasing fecal cholesterol excretion. It is believed that diosgenin promotes fecal cholesterol excretion by stimulating biliary cholesterol secretion and decreasing intestinal cholesterol absorption. Ni...

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Hlavní autoři: Temel, Ryan E., Brown, J. Mark, Ma, Yinyan, Tang, Weiqing, Rudel, Lawrence L., Ioannou, Yiannis A., Davies, Joanna P., Yu, Liqing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666178/
https://ncbi.nlm.nih.gov/pubmed/19141868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800631-JLR200
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