Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent

Diosgenin exists in some food supplements and herbal medicines and lowers plasma cholesterol by increasing fecal cholesterol excretion. It is believed that diosgenin promotes fecal cholesterol excretion by stimulating biliary cholesterol secretion and decreasing intestinal cholesterol absorption. Ni...

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Autors principals: Temel, Ryan E., Brown, J. Mark, Ma, Yinyan, Tang, Weiqing, Rudel, Lawrence L., Ioannou, Yiannis A., Davies, Joanna P., Yu, Liqing
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666178/
https://ncbi.nlm.nih.gov/pubmed/19141868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800631-JLR200
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