Acute Sterol O-Acyltransferase 2 (SOAT2) Knockdown Rapidly Mobilizes Hepatic Cholesterol for Fecal Excretion

The primary risk factor for atherosclerotic cardiovascular disease is LDL cholesterol, which can be reduced by increasing cholesterol excretion from the body. Fecal cholesterol excretion can be driven by a hepatobiliary as well as a non-biliary pathway known as transintestinal cholesterol efflux (TI...

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Bibliografiska uppgifter
Huvudupphovsmän: Marshall, Stephanie M., Gromovsky, Anthony D., Kelley, Kathryn L., Davis, Matthew A., Wilson, Martha D., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Rudel, Lawrence L., Brown, J. Mark, Temel, Ryan E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047063/
https://ncbi.nlm.nih.gov/pubmed/24901470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098953
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