Cholesterol Esters (CE) Derived from Hepatic Sterol O-Acyltransferase 2 (SOAT2) are Associated with More Atherosclerosis than CE from Intestinal SOAT2

RATIONALE: Cholesterol esters (CE), especially cholesterol oleate, generated by hepatic and intestinal sterol O-acyltransferase 2 (SOAT2) play a critical role in cholesterol homeostasis. However, it is unknown if the contribution of intestine-derived CE from SOAT2 would have similar effects in promo...

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Main Authors: Zhang, Jun, Sawyer, Janet K., Marshall, Stephanie M., Kelley, Kathryn L., Davis, Matthew A., Wilson, Martha D., Brown, J. Mark, Rudel, Lawrence L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209196/
https://ncbi.nlm.nih.gov/pubmed/25239141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.304378
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