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Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice

Deficiency of acyl CoA:cholesterol acyltransferase 2 (ACAT2) in mice results in a reduction in cholesterol ester synthesis in the small intestine and liver, which in turn limits intestinal cholesterol absorption, hepatic cholesterol gallstone formation, and the accumulation of cholesterol esters in...

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Detalhes bibliográficos
Main Authors: Willner, Emily L., Tow, Bryan, Buhman, Kimberly K., Wilson, Martha, Sanan, David A., Rudel, Lawrence L., Farese, Robert V.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298761/
https://ncbi.nlm.nih.gov/pubmed/12538880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0336398100
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