A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels

Altered cellular bioenergetics and mitochondrial function are major features of several diseases including cancer, diabetes, and neurodegenerative disorders. Given this important link to human health, we sought to define proteins within mitochondria that are critical for maintaining homeostatic ATP...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Lanning, Nathan J., Looyenga, Brendan D., Kauffman, Audra L., Niemi, Natalie M., Sudderth, Jessica, DeBerardinis, Ralph J., MacKeigan, Jeffrey P.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046887/
https://ncbi.nlm.nih.gov/pubmed/24767988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.065
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares