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Spectroscopic and Mechanistic Studies of Heterodimetallic Forms of Metallo-β-lactamase NDM-1

[Image: see text] In an effort to characterize the roles of each metal ion in metallo-β-lactamase NDM-1, heterodimetallic analogues (CoCo-, ZnCo-, and CoCd-) of the enzyme were generated and characterized. UV–vis, (1)H NMR, EPR, and EXAFS spectroscopies were used to confirm the fidelity of the metal...

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Autori principali: Yang, Hao, Aitha, Mahesh, Marts, Amy R., Hetrick, Alyssa, Bennett, Brian, Crowder, Michael W., Tierney, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046764/
https://ncbi.nlm.nih.gov/pubmed/24754678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja410376s
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