Investigating the position of the hairpin loop in New Delhi metallo-β-lactamase, NDM-1, during catalysis and inhibitor binding

In an effort to examine the relative position of a hairpin loop in New Delhi metallo-β-lactamase, NDM-1, during catalysis, rapid freeze quench double electron electron resonance (RFQ-DEER) spectroscopy was used. A doubly-labeled mutant of NDM-1, which had one spin label on the invariant loop at posi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Inorg Biochem
Prif Awduron: Aitha, Mahesh, Moller, Abraham J., Sahu, Indra D., Horitani, Masaki, Tierney, David L., Crowder, Michael W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843777/
https://ncbi.nlm.nih.gov/pubmed/26717260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2015.10.011
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