Intratracheal Bleomycin Causes Airway Remodeling and Airflow Obstruction in Mice

INTRODUCTION: In addition to parenchymal fibrosis, fibrotic remodeling of the distal airways has been reported in interstitial lung diseases. Mechanisms of airway wall remodeling, which occurs in a variety of chronic lung diseases, are not well defined and current animal models are limited. METHODS:...

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Hauptverfasser: Polosukhin, Vasiliy V., Degryse, Amber L., Newcomb, Dawn C., Jones, Brittany R., Ware, Lorraine B., Lee, Jae Woo, Loyd, James E., Blackwell, Timothy S., Lawson, William E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046254/
https://ncbi.nlm.nih.gov/pubmed/22394287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902148.2012.658595
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