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β-Catenin in the Alveolar Epithelium Protects from Lung Fibrosis after Intratracheal Bleomycin

Rationale: Alveolar epithelial cells (AECs) play central roles in the response to lung injury and the pathogenesis of pulmonary fibrosis. Objectives: We aimed to determine the role of β-catenin in alveolar epithelium during bleomycin-induced lung fibrosis. Methods: Genetically modified mice were dev...

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Main Authors: Tanjore, Harikrishna, Degryse, Amber L., Crossno, Peter F., Xu, Xiaochuan C., McConaha, Melinda E., Jones, Brittany R., Polosukhin, Vasiliy V., Bryant, Andrew J., Cheng, Dong-Sheng, Newcomb, Dawn C., McMahon, Frank B., Gleaves, Linda A., Blackwell, Timothy S., Lawson, William E.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733436/
https://ncbi.nlm.nih.gov/pubmed/23306543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201205-0972OC
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