Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis

Single-dose intratracheal bleomycin has been instrumental for understanding fibrotic lung remodeling, but fails to recapitulate several features of idiopathic pulmonary fibrosis (IPF). Since IPF is thought to result from recurrent alveolar injury, we aimed to develop a repetitive bleomycin model tha...

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Main Authors: Degryse, Amber L., Tanjore, Harikrishna, Xu, Xiaochuan C., Polosukhin, Vasiliy V., Jones, Brittany R., McMahon, Frank B., Gleaves, Linda A., Blackwell, Timothy S., Lawson, William E.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957416/
https://ncbi.nlm.nih.gov/pubmed/20562227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00026.2010
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