TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment

The response of alveolar epithelial cells (AECs) to lung injury plays a central role in the pathogenesis of pulmonary fibrosis, but the mechanisms by which AECs regulate fibrotic processes are not well defined. We aimed to elucidate how transforming growth factor-β (TGFβ) signaling in lung epitheliu...

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Main Authors: Degryse, Amber L., Tanjore, Harikrishna, Xu, Xiaochuan C., Polosukhin, Vasiliy V., Jones, Brittany R., Boomershine, Chad S., Ortiz, Camila, Sherrill, Taylor P., McMahon, Frank B., Gleaves, Linda A., Blackwell, Timothy S., Lawson, William E.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119129/
https://ncbi.nlm.nih.gov/pubmed/21441353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00397.2010
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