TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment

The response of alveolar epithelial cells (AECs) to lung injury plays a central role in the pathogenesis of pulmonary fibrosis, but the mechanisms by which AECs regulate fibrotic processes are not well defined. We aimed to elucidate how transforming growth factor-β (TGFβ) signaling in lung epitheliu...

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Autores principales: Degryse, Amber L., Tanjore, Harikrishna, Xu, Xiaochuan C., Polosukhin, Vasiliy V., Jones, Brittany R., Boomershine, Chad S., Ortiz, Camila, Sherrill, Taylor P., McMahon, Frank B., Gleaves, Linda A., Blackwell, Timothy S., Lawson, William E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119129/
https://ncbi.nlm.nih.gov/pubmed/21441353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00397.2010
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