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MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

Parkinson's disease (PD) genes PINK1 and parkin act in a common pathway that regulates mitochondrial integrity and quality. Identifying new suppressors of the pathway is important for finding new therapeutic strategies. In this study, we show that MUL1 suppresses PINK1 or parkin mutant phenotyp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yun, Jina, Puri, Rajat, Yang, Huan, Lizzio, Michael A, Wu, Chunlai, Sheng, Zu-Hang, Guo, Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044952/
https://ncbi.nlm.nih.gov/pubmed/24898855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01958
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