Llwytho...

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

Parkinson's disease (PD) genes PINK1 and parkin act in a common pathway that regulates mitochondrial integrity and quality. Identifying new suppressors of the pathway is important for finding new therapeutic strategies. In this study, we show that MUL1 suppresses PINK1 or parkin mutant phenotyp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yun, Jina, Puri, Rajat, Yang, Huan, Lizzio, Michael A, Wu, Chunlai, Sheng, Zu-Hang, Guo, Ming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044952/
https://ncbi.nlm.nih.gov/pubmed/24898855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01958
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