Cargando...

Pot1a Prevents Telomere Dysfunction and ATM-Dependent Neuronal Loss

Genome stability is essential for neural development and the prevention of neurological disease. Here we determined how DNA damage signaling from dysfunctional telomeres affects neurogenesis. We found that telomere uncapping by Pot1a inactivation resulted in an Atm-dependent loss of cerebellar inter...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lee, Youngsoo, Brown, Eric J., Chang, Sandy, McKinnon, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044246/
https://ncbi.nlm.nih.gov/pubmed/24899707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4245-13.2014
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!