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RPA and POT1: Friends or foes at telomeres?

Telomere maintenance in cycling cells relies on both DNA replication and capping by the protein complex shelterin. Two single-stranded DNA (ssDNA)-binding proteins, replication protein A (RPA) and protection of telomere 1 (POT1) play critical roles in DNA replication and telomere capping, respective...

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Bibliographic Details
Main Authors: Flynn, Rachel Litman, Chang, Sandy, Zou, Lee
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318101/
https://ncbi.nlm.nih.gov/pubmed/22373525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.4.19061
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