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Pot1a Prevents Telomere Dysfunction and ATM-Dependent Neuronal Loss
Genome stability is essential for neural development and the prevention of neurological disease. Here we determined how DNA damage signaling from dysfunctional telomeres affects neurogenesis. We found that telomere uncapping by Pot1a inactivation resulted in an Atm-dependent loss of cerebellar inter...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Society for Neuroscience
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4044246/ https://ncbi.nlm.nih.gov/pubmed/24899707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4245-13.2014 |
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