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In Vitro Rescue Study of a Malignant Familial Hypertrophic Cardiomyopathy Phenotype by Pseudo-Phosphorylation of Myosin Regulatory Light Chain

Pseudo-phosphorylation of cardiac myosin regulatory light chain (RLC) has never been examined as a rescue method to alleviate a cardiomyopathy phenotype brought about by a disease causing mutation in the myosin RLC. This study focuses on the aspartic acid to valine substitution (D166V) in the myosin...

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Sonraí Bibleagrafaíochta
Main Authors: Muthu, Priya, Liang, Jingsheng, Schmidt, William, Moore, Jeffrey R., Szczesna-Cordary, Danuta
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043912/
https://ncbi.nlm.nih.gov/pubmed/24374283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2013.12.011
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