Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer

Upregulation of fatty acid synthase (FASN), a key enzyme of de novo lipogenesis, is associated with metastasis in colorectal cancer (CRC). However, the mechanisms of regulation are unknown. Since angiogenesis is crucial for metastasis, we investigated the role of FASN in the neovascularization of CR...

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Detalhes bibliográficos
Main Authors: Zaytseva, Yekaterina Y., Elliott, Victoria A., Rychahou, Piotr, Mustain, W.Conan, Kim, Ji Tae, Valentino, Joseph, Gao, Tianyan, O’Connor, Kathleen L., Neltner, Janna M., Lee, Eun Y., Weiss, Heidi L., Evers, B.Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043242/
https://ncbi.nlm.nih.gov/pubmed/24510238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu042
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